Antibody Sequence Analysis Tool

CDR Based Analysis Full Length Based Annotation Sequence-based Clustering

CDR Based Analysis

The search will match sequences of the same length, using N-Gram indexing and LIKE search to find similar or contained sequences. Results will display Seq and CDR sequence.

Enter CDR Sequence

Invalid CDR sequence. Only standard amino acids (A, C, D, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, Y) are allowed.

CDR Numbering Scheme

Please select a CDR database.

CDR Type

Please select a CDR type.

Chain Type

Please select a chain type.

Example CDR Sequences:

Database: IMGT; CDR Type: CDR3; Chain Type: Heavy Chain; Sequence: CPDLDSSASWETLHV Database: IMGT; CDR Type: CDR3; Chain Type: Light Chain; Sequence: MQATHFPRT

Full Length Based Annotation

ANARCI-Based antibody DNA/Protein Annotation

Invalid sequence. Must be 50-500 characters, containing only valid DNA (A, T, C, G, -) or protein (A, C, D, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, Y) characters.

Sequence Type

Please select a sequence type.

Analysis Type

Please select an analysis type.

Example Protein Sequence:

EVQLVETGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARVKWELNLLLTTPSHYFDYWGQGTLVTVSS

Length: 126 aa

Type: Protein

Sequence-based Clustering

Perform clonal grouping and tree construction based on V/J germline gene usage and CDR3 sequence similarity

Invalid changeo. Must be 1-10 sequences in FASTA format, containing only valid DNA (A, T, C, G, -) characters in sequence parts.

Antibody Type Against Virus

Please select a virus type.

Example DNA sequence:

>68.02a.C.0134_1
GAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTACAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTCAGTAGCTACGACATGCACTGGGTCCGCCAAACTACAGGAAAAGATCTGGAGTGGGTCTCAGCTATTGGTACTGCTGGTGACACATACTATCCAGGCTCCGTGAAGGGCCGATTCACCATCTCCAGAGAAAATGCCAAGAACTCCTTGTATCTTCAAATGAACAGCCTGAGAGCCGGGGACACGGCTGTGTATTACTGTGCAAGAGGTGCTTTTGATAGTAGTGGTTTTTACAATTACTTTGACTACTGGGGCCAGGGAACGCTGGTCACCGTCTCCTCAG

>H1ssF|upper|P12|321-213-03_1B04_1
CAGGTGCAGCTGCTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTGTCCTGCAAGGCTTCTGGAGGCATCCTCAGAACACTTGCAATCAGCTGGGTGCGACAGGCCCCTGGACAAGGACTTGAGTGGATGGGAGGGATCATCGCTATCTTTGGAACAACAAACTACGCACAGAAATTCCAGGGCAGAGTCACGATTACCGCGGACGAATCCACGACCACAGTTTATATGGAGTTGAGCAGCCTCAGATCTGAGGACACGGCCGTGTATTACTGTGCGGGGGGGACTAAGAATTACCACTACGCCTACATGGACGTCTGGGGCACAGGGACCGCGGTCACCGTCTCCTCT

Sequnence nubmer: 3

Select Virus: SARS-CoV-2